Cortiva® 1mm allograft dermis offers precise thickness consistency and a range of size options, providing a predictable choice for exceptional handling.1,6,7,12,†,‡
Predictability is our focus. Cortiva® allograft dermis grafts are precisely controlled to ± 0.1mm, measured every 2cm increment.1
Cortiva® allograft dermis grafts feature a precise thickness consistency range compared to other leading acellular dermal matrixes of similar thickness.1 Comparison based on publicly available specifications.
Cortiva® allograft dermis, processed using a proprietary method that maintains the native dermal structure, has demonstrated rapid revascularization and remodeling to support graft incorporation.1,6,7,9,*,†
In pre-clinical studies, cellular infiltration and capillary formation were observed as early as 7 days post implantation along with a favorable immune response consistent with normal wound healing.1,*
In a clinical setting, 13 patients underwent a second planned procedure where the graft was biopsied, and robust revascularization and incorporation were observed.6,†
Images: Representative Masson’s Trichrome histology.
In a prospective randomized controlled trial of 302 patients, outcomes with Cortiva® 1mm allograft dermis (151 patients) were compared to outcomes with AlloDerm RTM (151 patients). The study noted that the odds of seroma formation were nearly twice as high with AlloDerm RTM than with Cortiva® 1mm allograft dermis (p=0.047) after adjustment for relevant covariates.7,†
Seroma
Hematoma
Infection
Necrosis
Dehiscence
Reconstructive failure
21 (7.6%)
4 (1.4%)
24 (8.7%)
17 (6.1%)
14 (5.1%)
23 (8.3%)
AlloDerm RTM
33 (12%)
10 (3.6%)
26 (9.3%)
22 (7.9%)
16 (5.7%)
26 (9.3%)
p-Value
0.09
0.17
0.80
0.43
0.73
0.68
Cortiva® 1mm Tailored allograft dermis is designed to enhance surgical precision and support patient-centric customization.11
With precise thickness consistency, Cortiva® 1mm allograft dermis provides a predictable option for excellent handling.1,6,7,12,†
Overview
The thinnest cut for exceptional pliability
Unique hexagonal perforations
Unique hexagonal perforations
For patient centric customization
Consistent thickness for predictable graft handling‡
Thickness
0.45–0.7mm thick
0.8–1.0mm thick
0.8–1.0mm thick
0.8–1.0mm thick
0.8–1.0mm thick
Rehydration
At least 30 seconds
At least 30 seconds
At least 30 seconds
At least 30 seconds
At least 30 seconds
Dermis
Dermis without basement membrane (no orientation)
Perforated dermis without basement membrane (no orientation)
Perforated dermis with basement membrane
Dermis without basement membrane (no orientation)
Dermis with basement membrane
Size
2×4cm to 16×20cm
Small, Medium, Large
16×20cm
Small, Medium, Large
4×12cm to 16x20cm